Web-accessible database of residue-level structural-functional annotations of nicotinic acetylcholine receptors

NAChRDB is particularly useful for identifying gaps in knowledge and for guiding discovery through structural and molecular biology experiments, especially when exploring the allosteric mechanisms underlying neuromuscular nAChR function and pathology.

NAChRDB contains annotations from published and unpublished studies. The relationship between publication and validation is central to the mission of NAChRDB, which is not to grant credibility to the reports, but rather to create the perfect venue for assessing the credibility of reports in the proper context of the knowledge accumulated so far.

What research questions can be answered using NAChRDB?

Last update:

When using NAChRDB, please cite:

Chareshneu, A.; Pant, P.; Tristão Ramos, R. J.; Sehnal, D.; Gökbel, T.; Ionescu, C.-M.; Koča, J. NAChRDB: A Web Resource of Structure–Function Annotations to Unravel the Allostery of Nicotinic Acetylcholine Receptors. ACS Omega 2021, 6, 23023–23027. DOI: 10.1021/acsomega.1c00817.

In memory of professor Jaroslav Koča

Interested? Feel free to contact us by email: 479052@mail.muni.cz

License conditions in accordance with § 11 of Act No. 130/2002 Coll. The owner of the software is Masaryk University, a public university, ID: 00216224. Masaryk University allows companies and individuals to use this software free of charge and without territorial restrictions, in a manner that does not depreciate its value. This permission is granted for the duration of property rights. This software is not subject to special information treatment according to Act No. 412/2005 Coll., as amended. If a person who uses the software under this license offer violates the license terms, the permission to use the software is terminated.